Truly a classic in my humble opinion.  

Not being a huge vampire film fan, I was unsure about this film when I first saw it years ago.  It has become one of my all time favorites over the years.  It has all of the great elements of horror and a load of gore.  As far as horror goes, you will be hard pressed to find one with more action.

Seth Gecko (George Clooney) and Richard Gecko (Quentin Tarantino) are criminal brothers trying to get to Mexico.  They wind up essentially taking the Fuller family (Juliette Lewis, Harvey Keitel and Ernest Liu) hostage and force them to drive them to Mexico.  Cheech Marin plays several different characters in the film as well.

Jacob Fuller (Keitel) is a former pastor who finds himself completely disgruntled with God.  He and his family find their road trip cut short when they have the misfortune of running into the Gecko brothers.

Without giving too much away, Seth Gecko directs everyone to a meeting place in Mexico.  Unfortunately for everyone involved, the nudie bar is crawling with vampires and there is no way out.  Enter Santanico Pandemonium (Salma Hayek) as the hottest vampire ever on film.  Once she turns, the proverbial crap hits the fan like few other movies.  From this point on, the action and gore are nearly non-stop.  Few horror films have ever successfully maintained such a pace.  Keitel is awesome as the "faithless preacher" turned "mean mother f'ing servant of God".  And what young man hasn't dreamed of being Seth Gecko after seeing George Clooney in this role?  Truly a badass.  Yet a moral badass.

If you are familiar with Tarantino and director Robert Rodriguez (Planet Terror, Machete and Sin City to name just a few), then you likely can envision the gore that flows in this film.  The dialogue is phenomenal and the acting is excellent.  In fact, I cannot find any real weakness with this film. It is simply fun from start to finish.  A true horror classic in every sense of the word.